Thalamocortical synapses with corticothalamic projection neurons in mouse SmI cortex: electron microscopic demonstration of a monosynaptic feedback loop.

نویسندگان

  • S M Hersch
  • E L White
چکیده

Synapses between degenerating thalamocortical axon terminals and corticothalamic projection neurons labeled by the retrograde transport of horseradish peroxidase have been identified in mouse Sml cortex. This monosynaptic thalamocortical-corticothalamic feedback loop is suggested to be involved in reinforcing differences in the levels of excitation between parallel components of thalamocortical projections.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A quantitative study of thalamocortical and other synapses involving the apical dendrites of corticothalamic projection cells in mouse SmI cortex.

Lesion-induced degeneration was combined with the retrograde transport of horseradish peroxidase (HRP) to examine the thalamocortical and other synaptical relationships of corticothalamic projection cells in mouse SmI cortex. Injections containing 40% HRP were placed in the ventrobasal thalamus and the next day, electrolytic lesions were made of the injection site. About four days later, the an...

متن کامل

THE JOURNAL OF COMPARATIVE NEUROLOGY 198:167-181 (1981) Thalamocortical Synapses of Pyramidal Cells Which Project From Sml to Msl Cortex in the Mouse

Electrolytic lesions were made of the nucleus ventralis posterior pars lateralis thalami and of the nucleus posterior thalami in male CD/1 mice to label thalamocortical axon terminals in mouse SmI cortex. Pyramidal cells in layers I1 through V of SmI cortex were labeled by the retrograde transport of horseradish peroxidase injected into ipsilateral MsI. Numerous pyramidal cells, particularly in...

متن کامل

VPM and PoM nuclei of the rat somatosensory thalamus: intrinsic neuronal properties and corticothalamic feedback.

Sensory information originating in individual whisker follicles ascends through focused projections to the brainstem, then to the ventral posteromedial nucleus (VPM) of the thalamus, and finally into barrels of the primary somatosensory cortex (S1). By contrast, the posteromedial complex (PoM) of the thalamus receives more diffuse sensory projections from the brainstem and projects to the inter...

متن کامل

A quantitative study of the thalamocortical and other synapses in layer IV of pyramidal cells projecting from mouse SmI cortex to the caudate-putamen nucleus.

The thalamocortical and other synapses of the apical dendrites of corticostriatal projection neurons in mouse primary somatosensory cortex (SmI) were examined by combining anterograde degeneration with the retrograde transport of horseradish peroxidase (HRP). Electrolytic lesions were made in the ventrobasal thalamus, followed 3 days later by injections of 40% HRP into the ipsilateral caudate-p...

متن کامل

The identification of thalamocortical axon terminals in barrels of mouse Sml cortex using immunohistochemistry of anterogradely transported lectin (Phaseolus vulgaris-leucoagglutinin).

The anterograde transport and immunohistochemical demonstration of the lectin, Phaseolus vulgaris-leucoagglutinin (PHA-L) has been used to label thalamocortical axon terminals in barrels of mouse SmI cortex. The reaction product is visible with both the light and electron microscopes so that the distribution of axons and the types of synapses they form can be determined.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Neuroscience letters

دوره 24 3  شماره 

صفحات  -

تاریخ انتشار 1981